No, I have never tried primrose oil. As I've been on this journey of success and failures, I'm pretty sure I've learned that my body (perhaps all ich sufferers) have trouble digesting fats. Healthy fats are essential for healthy skin. Vitamin A is a fat soluble vitamin which is why it can be toxic to take too much. Water soluble vitamins can be released in our urine, but fast soluble vitamins can be stored up in our bodies. Maybe my struggle in digesting fats is one of the reasons that taking larger amounts is necessary... absorbing what most people would get in smaller amounts. Who knows? I really have more questions than answers, but at the moment I'm supplementing my fat meals with ox bile to see if that helps.