I don't know anything about the center, but Avene Trixera products have been miraculous for my son. Warning: they are not cheap! But we've been using them for almost a year and they've made quite a difference for him. We use Avene Trixera Emollient Bath twice a day - fill up the tub with lukewarm water and dilute 1/2 a capful - and have him sit in it for three minutes, no more. Then pull him out, peel off any skin that's ready to come off, pat him dry and slather on Avene Trixera Cream. His skin has come a long way since we started doing this.