Hi, I'm a 20 yr old female with Lamellar ichthyosis and I've been taking Soriatane for about 4 yrs. So far the side effects have been worth it! ( peeling hands, dry eyes) and I haven't really experienced many other side effects. I get a blood test every couple of months, and I've gotten xrays which show that everything seems to be fine. I would love to hear from anyone taking Soriatane or with LI!