Originally posted by Xander:
Hello everyone. I have read a few studies regarding treatment with 10% N-acetylcysteine in a water silicone emulsion. Does anyone have any personal experience with this treatment?
Your post brought up an interesting approach to treatment that I have never considered myself. That is the regular use of antioxidants *topically* to treat ich. I eat plenty of foods rich in antioxidants and take several supplements. I find my skin condition to be better than before, but I can't say whether that is just from better nutrition overall or specifically from the a-o's. If you do try either the 10% N-A treatment or the Remedy products on your daughter, please post about back about the results. I, for one, would be very interested to know about it.
As for your question on the 10% N-A emulsion, there has been a previous post about it. If you haven't already seen it I've linked it below. http://www.ichthyosis.com/ubb/Forum1/HTML/000181.html
For others who may be interested, I've copied a synopsis of the 1999 Spanish case study.
Antioxidant emulsion cures scaly skin (ichthyosis)
PAMPLONA, SPAIN. Ichthyosis is a condition in which the skin is dry, rough, and scaly. It is caused by a fault in the control mechanism which governs the deposition of keratin (a fibrous protein) in the skin and is often present at birth (congenital). Ichthyosis can be ameliorated somewhat by the use of emollient creams, bath oils and ointments, but the condition is usually an ongoing problem. Medical doctors at the University Clinic of Navarra, School of Medicine now report the successful treatment of ichthyosis with a water-in-oil (silicone) emulsion containing 10 per cent of N-acetylcysteine (NAC). Their patient, a 33- year-old woman, had large patches of dark, scaly skin on her limbs, trunk, scalp, and neck and had been treated with conventional therapies without success. She was instructed to apply the NAC emulsion to one of her forearms and a placebo emulsion (without the NAC) to the other forearm twice a day. Five weeks later the skin on the arm treated with the NAC emulsion was essentially free of scales and roughness while no change was observed on the arm which had received the placebo treatment. The researchers conclude that a NAC-containing water-in-silicone emulsion may be useful in the treatment of hyperproliferative skin disorders and point out that NAC is hypoallergenic, non-toxic, and rarely has any side effects.
Redondo, Pedro and Bauza, Ana. Topical N-acetylcysteine for lamellar ichthyosis. The Lancet, Vol. 354, November 27, 1999, p. 1880 (research letter)