Thanks for your reply Les. I am surprised that double blind and/or placebo-based trials were used for Lacloction. I wouldn't have thought that necessary for topical cream testing. I would think that skin improvement is visually obvious and not a product of clinical suggestion or psychosomatic effects. (and what would they give you anyway? a "sugar lotion" similar to a "sugar pill" placebo...these questions are rhetorical [img]http://www.ichthyosis.com/ubb/smile.gif
The active, and presumably risk-causing, ingredients appear to be identical in Lachydrin and Amlactin. Whereas even 25% urea and 12% lactic acid creams are not deemed to pose a risk of harm or abuse to the Canadian public or to drug effectiveness/resistance, I don't know why in the US lacydrin is categorized as it is, particularly if Amlactin is OTC in the US. As for the higher prices, it's a product of competition (there are for more acid lotions available on the Canadian market OTC that aren't on the US market) and the culture of 'higher prices for US customers' that seems to pervade all sectors of the pharmaceutical industry.
As far I can quickly glean from several of the online pharmacy sites, if the product is OTC in Canada then no presciption is need for orders from outside Canada, even if the same item is a prescription medication in the recipient's jurisdiction. Anyone ordering from the US should however ensure that the online pharmacy is one with integrity. There are unlicenced or unscrupulous pharmacies that purport to be Canadian, while actually based in another country.
Trial and error is indeed the only way to find what best suits an individual's personal preference and skin needs for each the different types of ICH. My father, sister and I all have IV and we each have our own lotions of choice. At the same time there are some universal principles of skin care that apply to all three of us.
[This message has been edited by gryphon (edited June 03, 2006).]