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#28075 - 11/17/11 08:13 PM Newly pregnant, questions about LI
Janica16 Offline
New member

Registered: 11/17/11
Posts: 2
I just found out I am 5weeks pregnant..hooray! I have lamellar ich and my husband has no family history of a skin issue. What are the odds my child will also have LI? Also, I use PDS cream from neoceuticals and amlactin, can anyone tell me if these are safe to use while pregnant? Thank you!!

#28076 - 11/17/11 10:43 PM Re: Newly pregnant, questions about LI [Re: Janica16]
Hearsay Offline


Registered: 01/16/04
Posts: 1449
Loc: Richmond, VA, USA
Your odds of passing it along are very low. 100% chance that your babies will all be carriers. However, the odds that your husband is a carrier is 1/250. If he is, there's a 1/2 chance of passing along the LI mutation and a 1/2 chance of passing on a normal gene.

So: 1/250 x 1/2 x 1/1 = 1/500 chance of passing it to your child.

If on the off chance he really is a carrier, which you won't know until after you have a baby that's affected or go through genetic testing with him, then the odds are

1/2 (him) x 1/1 (you) = 1/2 kids affected, 1/2 kids carriers.

Also, if he's a carrier for any other skin mutation gene than the one you have, your child won't have ichthyosis. So if you have, say, TGM1 mutation, and he carries a mutation for ICHTHYIN, your child would only be a carrier and not affected.
Ichthyosis-en-Confetti Type 2
Husband, Nathan - 10, Elliot - 7, Oliver - 4, all affected.
I also have an unaffected daughter, age 8.

email: jennifer at confettiskin dot com
facebook - find me on "ichthyosis mommy spot" or "friends of ichthyosis"


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