No. We tried with both pregnancies. Harlequin is visible on ultrasound.
Confetti, as we have, is a type of EHK. We had a suggestion of ichthyosis on a very high resolution ultrasound done at a specialist's office. We could see a lot of particulate matter in the amniotic flud and we attempted to measure the scalp thickness, but it was inconclusive. We also tried to look at the cracking pattern on the feet, but that, too, was not visible on our boys. Ultrasounds were done around 32-33 weeks.
If you are looking for collodion, it is too thin to be visible and any stiffness wouldn't appear until the baby is out of the amniotic fluid.
If you are looking for XLI, the sure-fire test is the steroid sulfatase test.
Keep in mind that the skin doesn't develop into layers until about 30 weeks gestation. You can't see ANYTHING on any child of any type at the normal 20 week scan.
Ichthyosis-en-Confetti Type 2
Husband, Nathan - 10, Elliot - 7, Oliver - 4, all affected.
I also have an unaffected daughter, age 8.
email: jennifer at confettiskin dot com
facebook - find me on "ichthyosis mommy spot" or "friends of ichthyosis"