My husband and son both have EHK. We started using a Dremel sander on my husband's feet 2 years ago. Before that he was hacking off the calluses with a pocket knife. He says that this hurts much less and is much more efficient and precise.
He originally started using it on his feet dry, but because the skin is so thick the heat builds up and it burns. He has found that it works best right after his shower - he puts towels along the door of the shower and one on the floor to catch all the dust. He sands, then removes the towels and Dremel and washes the loose dust off, then gets out and creams as usual. He does it 1-2x a month.
The only caveat is that it changes his ability to walk for a day or two until his he adjusts to the new balance.
I have used it once on our 1 year old, but he is not as severe as his dad, so it isn't as necessary.
Ichthyosis-en-Confetti Type 2
Husband, Nathan - 10, Elliot - 7, Oliver - 4, all affected.
I also have an unaffected daughter, age 8.
email: jennifer at confettiskin dot com
facebook - find me on "ichthyosis mommy spot" or "friends of ichthyosis"